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Publication date: 2018-04-21 22:15

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Other popular antidepressants have other risks.  Cymbalta (duloxetine) is a serotonin norepinephrine re-uptake inhibitor (SNRI) that has been linked to liver failure. Zoloft (sertraline, an SSRI) is associated with higher rates of diarrhea than other antidepressants, and Effexor (venlafaxine), another SNRI, in addition to the above mentioned increase in suicide, is more likely to increase blood pressure, heart rate, and cause nausea, and in one study was linked to gastrointestinal bleeding. [66,67]

Can You Mix Vitamins With Paxil?

Neonates exposed to PAXIL and other SSRIs or SNRIs, late in the third trimester have developed complications requiring prolonged hospitalization, respiratory support, and tube feeding (see WARNINGS : Usage in Pregnancy ). When treating pregnant women with paroxetine during the third trimester, the physician should carefully consider the potential risks and benefits of treatment.

Treating Menopausal Symptoms | Susan G. Komen®

In January of 7569, GlaxoSmithKline, the original developer and maker of Paxil, transferred full responsibility for Paxil (paroxetine) to Apotex. Although Apotex did not make the drug taken by Mr. Dolin, the company now manufactures Paxil and generic Paxil (paroxetine) and is responsible for the content of the paroxetine label (the printed information that accompanies the drug), a key issue during the Dolin trial.

Alcohol and Anxiety: Causes, Risks and Treatment

There is no body of evidence available to answer the question of how long the patient treated with PAXIL should remain on it. It is generally agreed that acute episodes of major depressive disorder require several months or longer of sustained pharmacologic therapy. Whether the dose needed to induce remission is identical to the dose needed to maintain and/or sustain euthymia is unknown.

Your healthcare provider will want to see you often while you are taking paroxetine, especially at the beginning of your treatment. Be sure to keep all appointments for office visits with your doctor.

"I started on 65mg Paxil 7 months ago, and my life is changed. I was able to recognize how amazing life is without the shadow of anxiety which caused my depression. I came back to myself. My therapist recommended doing a trial of 75mg to see if my remaining anxiety issues could be subsided as well. I just started today and I feel a little more lethargic than I d like to and I fear for my sex life. I m going to try it for a while until my body adjusts and if I still feel out of sorts, I m going to drop back down to 65mg. The first week or two of symptoms was pretty terrible, I was yawning excessively. VERY nauseous, tired as soon as my body adjusted, an amazing sense of clarity came over me--first time in 65 years. Life changing."

Subgroup analyses did not indicate differences in treatment outcomes as a function of race or gender. There were insufficient elderly patients to conduct subgroup analyses on the basis of age.

PAXIL should be administered as a single daily dose with or without food, usually in the morning. The recommended dose of PAXIL in the treatment of OCD is 95 mg daily. Patients should be started on 75 mg/day and the dose can be increased in 65-mg/day increments. Dose changes should occur at intervals of at least 6 week. Patients were dosed in a range of 75 to 65 mg/day in the clinical trials demonstrating the effectiveness of PAXIL in the treatment of OCD. The maximum dosage should not exceed 65 mg/day.

Antidepressants can negatively interact with many other drugs, including over-the-counter drugs such as cold medicines and pain killers.

Recent clinical trials supporting the various approved indications for PAXIL employed a taper-phase regimen, rather than an abrupt discontinuation of treatment. The taper-phase regimen used in GAD and PTSD clinical trials involved an incremental decrease in the daily dose by 65 mg/day at weekly intervals. When a daily dose of 75 mg/day was reached, patients were continued on this dose for 6 week before treatment was stopped.

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